Funding Opportunity: Complex Traumatic Brain Injury Rehabilitation Research (CTRR) Program Announcement Clinical Trial Award (CTA) and Clinical Research Award (CRA)

Applications are encouraged to address one or more of the following FY19 PH/TBIRP CTRR Areas of Emphasis:

• • • Objective outcome measures of brain impairment after mTBI using existing U.S. Food and Drug Administration (FDA)-cleared devices (offered in CTA and CRA)
      • Develop objective measure(s) of brain function that determines severity of functional impairment
      • Correlate brain function to RTD performance
    • Optimization of treatment strategy based on patient classification to improve management of patients with mTBI as described above (offered in CTA and CRA)
      • • Determine indicators of successful recovery following mTBI
        • Validate algorithms for multi-modal treatment strategies
    • Return-to-Duty (RTD) risk assessment; computational model development or validation (offered in CRA only)
      • Integrate objective mild TBI (mTBI) patient data from multiple domains through computational modeling to inform RTD capability
      • Clinical support tool leveraging computational modeling to measure and communicate risk associated with returning injured Warfighters to duty following mTBI

Projects focused on other research areas relevant to the intent of the CTRR-CTA or CRA may be submitted for consideration, provided sufficient justification is included in the application.

Applications without clinical trials should be submitted under the FY19 PH/TBIRP CTRR Clinical Research Award (Funding Opportunity Number W81XWH-19-CTRR-CRA).

Detailed information about applying and copies of the program announcement can be found on grants.gov or
https://www.grants.gov/web/grants/view-opportunity.html?oppId=318656
https://www.grants.gov/web/grants/view-opportunity.html?oppId=318673

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.orgprior to the pre-application deadline. All applications must conform to the final Program Announcement and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms will also be found on Grants.gov

Point of Contact:
CDMRP Public Affairs 301-619-9783 usarmy.detrick.medcom-cdmrp.mbx.cdmrp-public-affairs@mail.mil